Due to advances in medical care, we are living longer. BUT ARE WE LIVING HEALTHIER? This is the crux of HEALTHSPAN, which can be defined as the amount of time lived free of disease. CELLULAR SENESCENCE Senescent cells (Sncs) accumulate in tissues as we age thus accelerating the ageing process and age-related diseases such as cancer, arthritis and bone loss, muscle loss (sarcopenia) and frailty, cardiovascular disease, pulmonary disease, diabetes, neurological disorders or dec